bcr: B-Cell receptor signalling perturbations

In MartinFXP/B-NEM: Training of logical models from indirect measurements of perturbation experiments

B-Cell receptor signalling perturbations

Description

Processed data from experiments with a stimulated B-Cell receptor (bcr) and perturbed signalling genes. The raw data is available at https://www.ncbi.nlm.nih.gov/geo/ with accession id GSE68761. For the process steps we refer to the publication Martin Pirkl, Elisabeth Hand, Dieter Kube, Rainer Spang, Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models, Bioinformatics, Volume 32, Issue 6, 15 March 2016, Pages 893–900, https://doi.org/10.1093/bioinformatics/btv680. Alternatively see also the function processDataBCR for details and for reproduction.

Usage

bcr

References

Martin Pirkl, Elisabeth Hand, Dieter Kube, Rainer Spang, Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models, Bioinformatics, Volume 32, Issue 6, 15 March 2016, Pages 893–900, https://doi.org/10.1093/bioinformatics/btv680

Examples

data(bcr)

MartinFXP/B-NEM documentation built on Oct. 27, 2023, 8:24 p.m.