read_fusion: Format univariate FUSION TWAS output across multiple traits...
In MichelNivard/GenomicSEM: Structural equation modeling based on GWAS summary statistics
read_fusion R Documentation
Format univariate FUSION TWAS output across multiple traits for subsequent use in a multivariate TWAS [T-SEM]
Description
Function to format TWAS summary statistics for T-SEM
Usage
read_fusion(files,trait.names=NULL,binary=NULL,N=NULL,perm=FALSE, ...)
Arguments
files
List of FUSION files.
trait.names
What names to use when naming the beta and SE columns for each trait
binary
Vector specifying whether each trait is binary (TRUE) or continuous (FALSE)
N
The sample size to use when backing out the betas and SEs from FUSION Z-statistics. This should reflect the sum of effective sample size for binary traits
perm
Whether you want to use the permutation test p-values from FUSION. Default = FALSE
Value
The function combines and formats FUSION TWAS summary statistics for subsequent T-SEM analyses.
The function returns a single data.frame.
MichelNivard/GenomicSEM documentation built on June 15, 2024, 10:41 a.m.
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| read_fusion | R Documentation |
Format univariate FUSION TWAS output across multiple traits for subsequent use in a multivariate TWAS [T-SEM]
Description
Function to format TWAS summary statistics for T-SEM
Usage
read_fusion(files,trait.names=NULL,binary=NULL,N=NULL,perm=FALSE, ...)
Arguments
files |
List of FUSION files. |
trait.names |
What names to use when naming the beta and SE columns for each trait |
binary |
Vector specifying whether each trait is binary (TRUE) or continuous (FALSE) |
N |
The sample size to use when backing out the betas and SEs from FUSION Z-statistics. This should reflect the sum of effective sample size for binary traits |
perm |
Whether you want to use the permutation test p-values from FUSION. Default = FALSE |
Value
The function combines and formats FUSION TWAS summary statistics for subsequent T-SEM analyses. The function returns a single data.frame.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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