PDiracDelta/CONSTANd: Data normalization by matrix raking

Normalizes a data matrix `data` by raking (using the RAS method by Bacharach, see references) the Nrows by Ncols matrix such that the row means and column means equal 1. The result is a normalized data matrix `K=RAS`, a product of row mulipliers `R` and column multipliers `S` with the original matrix `A`. Missing information needs to be presented as `NA` values and not as zero values, because CONSTANd is able to ignore missing values when calculating the mean. Using CONSTANd normalization allows for the direct comparison of values between samples within the same and even across different CONSTANd-normalized data matrices.

Getting started

Package details

Bioconductor views Cheminformatics DifferentialExpression Genetics MassSpectrometry Normalization Preprocessing Proteomics Transcriptomics
Maintainer
Licensefile LICENSE
Version0.99.6
URL qcquan.net/constand
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("PDiracDelta/CONSTANd")
PDiracDelta/CONSTANd documentation built on March 9, 2021, 11:47 a.m.