combination_index: compute combination index

In Peyronlab/MACSQuantifyR: Fast treatment of MACSQuantify FACS data

Description

This function allows the user to compute combination index on the drug combinations. This function also generates intermediary plots and tables.

Usage

combination_index(MACSQuant, ...)

Arguments

MACSQuant	object of class MACSQuant resulting of the function load_maxQuant(). Contains the original data table
...	params for lattice cloud namely z and x for parameter screen default for z and x are c(-110,-70) and argument xlab and ylab

Value

Several plots and combination index

References

Chou, T. C. (2006). Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies. Pharmacological reviews, 58(3), 621-681.

Examples

filepath <- system.file("extdata", "drugs.Rdata",
    package = "MACSQuantifyR")
load(filepath)
combination_index(MACSQuant)

Peyronlab/MACSQuantifyR documentation built on April 4, 2020, 11:24 a.m.