Roestlab/DIAlignR: Dynamic Programming Based Alignment of MS2 Chromatograms

To obtain unbiased proteome coverage from a biological sample, mass-spectrometer is operated in Data Independent Acquisition (DIA) mode. Alignment of these DIA runs establishes consistency and less missing values in complete data-matrix. This package implements dynamic programming with affine gap penalty based approach for pair-wise alignment of analytes. A hybrid approach of global alignment (through MS2 features) and local alignment (with MS2 chromatograms) is implemented in this tool.

Getting started

Package details

AuthorShubham Gupta <>, Hannes Rost <>
Bioconductor views Alignment MassSpectrometry Metabolomics Proteomics Software
MaintainerShubham Gupta <>
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
Roestlab/DIAlignR documentation built on March 3, 2021, 9:09 a.m.