signature: Mutational signatures data from COSMIC, Catalogue Of Somatic...

In Rozen-Lab/cosmicsig: Mutational Signatures from COSMIC (Catalogue of Somatic Mutations in Cancer)

Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.3 - June 2022)

Description

Mutational signatures data from COSMIC, Catalogue Of Somatic Mutations In Cancer (v3.3 - June 2022)

Usage

signature

Format

A list with the following elements:

• GRCh37: Homo sapiens (human) genome assembly GRCh37.

• GRCh38: Homo sapiens (human) genome assembly GRCh38.

• mm9: Mus musculus (house mouse) genome assembly mm9.

• mm10: Mus musculus (house mouse) genome assembly mm10.

• rn6: Rattus norvegicus (Norway rat) genome assembly rn6.

Each element contains the sub elements:

• SBS96: Strand-agnostic single-base substitutions in trinucleotide context.

• DBS78: Strand-agnostic doublet-base substitutions.

Element GRCh37 contains the additional sub elements:

• ID: Strand-agnostic indels (short insertions and deletions).

Remark

The signatures are all genome signatures.
See CatalogRowOrder in package ICAMS for the classification of mutation types.

Source

https://cancer.sanger.ac.uk/signatures/.

Examples

sbs96_sig <- signature$GRCh37$SBS96

Rozen-Lab/cosmicsig documentation built on Sept. 3, 2023, 8:50 a.m.