ShengLi/edmr: Empirical Differentially Methylated Regions Calculation

Optimized DMR analysis based on bimodal normal distribution model and cost function for regional methylation analysis optimization. It captures the regional methylation modification by taking the spatial distribution of CpGs into account for the enrichment DNA methylation sequencing data so as to optimize the definition of the empirical regions. Combined with the dependent adjustment for regional p-value combination and DMR annotation.

Getting started

Package details

AuthorSheng Li [aut, cre, cph], Francine Garrett-Bakelman [ctb], Altuna Akalin [ctb], Paul Zumbo [ctb], Ari Melnick [ctb], Chris Mason [ctb, ths]
MaintainerSheng Li <shelly1436@gmail.com>
LicenseArtistic-2.0
Version0.6.4.1
URL https://github.com/ShengLi/edmr
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("ShengLi/edmr")
ShengLi/edmr documentation built on May 9, 2019, 1:25 p.m.