estss: Estimate the specificity and sensitivity of a somatic...

In Sun-lab/SAME: Somatic mutation Association test with Measurement Errors

Estimate the specificity and sensitivity of a somatic mutation based on its read-count data.

Description

Estimate the specificity and sensitivity of a somatic mutation based on its read-count data.

Usage

estss(A, D, O, pi, varphi)

Arguments

A	A vector for the number of alternative reads for the somatic mutation.
D	A vector for the read-depths for the somatic mutation.
O	A vector for the observed somatic mutation values.
pi	The mean parameters for the beta-binomial distributions when the true somatic mutation value equals 0 or 1.
varphi	The over-dispersion parameters for the beta-binomial distributions when the true somatic mutation value equals 0 or 1.

Value

The estimated specificity and sensitivity for the somatic mutaiton.

Sun-lab/SAME documentation built on Jan. 27, 2024, 6:48 p.m.