This function takes a DATA.FRAME/ TXT file with the TFBS coverage data and estimates the Accesibility score as the range between the global maximum and minimum of the high-frequency signal. In order, to estimate the high-frequency signal, and remove the local biases the Savitzky-Golay filter is used.
1 | accessibility_score(data = "", output_dir = "", plot = TRUE, verbose = FALSE)
|
data |
DATA.FRAME with data or Path to TXT file |
output_dir |
Directory to output results. If not provided then outputs in current directory |
plot |
Create a plot with frequency data. Default TRUE. |
verbose |
Enables progress messages. Default FALSE |
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