CRM: Continual Reassessment Method (CRM) with Multiple Toxicity...
In XiaoqiLu/CRMplus:

Continual Reassessment Method (CRM) with Multiple Toxicity Constraints

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CRM(param.ini = NULL, dose, tox, skeleton, target,
  working.model = "power", cohort.size = 1,
  allow.dose.skipping = FALSE, allow.escalation.on.toxicity = FALSE)

`param.ini`	initial value of paramameter, default = rep(0, L)
`dose`	dose level sequence
`tox`	toxicity sequence
`skeleton`	mapped skeleton for dose levels, a vector of length = # of dose levels (K), should be between 0 and 1
`target`	targets for (cumulative) toxicity rates, a vector of length = # of toxicity levels (L)
`working.model`	working model, character, default = "power" (currently only supports "power")
`cohort.size`	default = 1
`allow.dose.skipping`	default = FALSE
`allow.escalation.on.toxicity`	default = FALSE