BJdata: Blood micro RNA Expression and Lung Function Data in Beijing...

In YinanZheng/PGS: Penalized GEE with Grid Search

Description

Blood micro RNA (miRNA) expression data of 166 miRNAs and lung function (FEV1) data of 120 individuals with two measurements in Beijing Air Pollution Study.

Usage

BJdata()

Format

BJmirna is a data frame of size 240 by 168. BJlung is a data frame of size 240 by 13.

Details

The data set BJmirna contains:

• SID: study subject ID

• WD: indicator of examination days

• 166 blood miRNA expression data

Blood samples were collection after work one the examination days.

The data set BJlung contains:

• SID: study subject id

• WD: indicator of examination days,

• FEV1: lung function measured by forced expiratory volume in 1 second

• pm25: air pollution measured by particulate matter up to 2.5 micrometers in size

• gender: gender

• age: age

• bmi: body mass index

• heat: use of central heating system

• cigwear: smoke cigarette during examination day

• waytime:commute time

• workhr: working hours

• dewp: humidity measured by dew point

• temp: temparature

All variables were measured during the examination days.

References

Hou L, Barupal J, Zhang W, et al. (2015) Environmental health perspectives. (PubMed)

Baccarelli AA, Zheng Y, Zhang X, et al. (2014) Particle and fibre toxicology. (PubMed)

Examples

### Dataset preview
BJdata()

### Convert binary variables into factor type. 
BJlung$gender = factor(BJlung$gender)
BJlung$heat = factor(BJlung$heat)
BJlung$cigwear = factor(BJlung$cigwear)

### Merge miRNA and lung function dataset.
BJdata <- merge(BJmirna, BJlung, by=c("SID","WD"))

### Sort the data by study subject id and multiple measurement indicator.
BJdata <- BJdata[with(BJdata, order(SID, WD)), ]

#For more information, please visit: https://github.com/YinanZheng/PGS/wiki/Example:-miRNA-expression-and-lung-function

YinanZheng/PGS documentation built on May 29, 2021, 10:07 p.m.