inst/aoas_simulations/README.md

In amcdavid/HurdleNormal: 'Estimation and sampling for multi-dimensional Hurdle models on a Normal density with applications to single-cell co-expression'

Steps to reproduce simulations and networks "Graphical Models for Zero-Inflated Single Cell Gene Expression"

Install HurdleNormal (eg with devtools::install_github) with dependencies = TRUE and install netbenchmark, Mus.musculus from bioconductor.

For simulations: 1. source simulations.R 2. Run processSimulations.Rmd

For networks generated from Shalek et al data:

1. Run fitAlex.R
2. Run processShalekMAITNetworks.Rmd

For networks generated from TFh data, the source data is as-yet unpublished a primary journal so cannot yet be made available publically.

amcdavid/HurdleNormal documentation built on May 14, 2022, 11:12 p.m.