Bayesian modelling of cell-to-cell DNA methylation heterogeneity

bb_mle | Beta binomial maximum likelihood estimation (BB MLE) |

create_design_matrix | Create design matrix |

sce_to_scmet | Convert from SingleCellExperiment to scmet object |

scmet | Perform inference with scMET |

scmet_diff_dt | Synthetic methylation data from two groups of cells |

scmet_differential | Differential testing using scMET |

scmet_dt | Synthetic methylation data from a single population |

scmet_hvf_lvf | Detect highly (or lowly) variable features with scMET |

scMET-package | 'scMET': Bayesian modelling of DNA methylation at single-cell... |

scmet_plot_efdr_efnr_grid | Plot EFDR/EFNR grid |

scmet_plot_estimated_vs_true | Plot true versus inferred parameter estimated. |

scmet_plot_ma | MA plot for differential analysis |

scmet_plot_mean_var | Plotting mean-variability relationship |

scmet_plot_vf_tail_prob | Plot tail probabilities for variable feature analysis |

scmet_plot_volcano | Volcano plot for differential analysis |

scmet_simulate | Simulate methylation data from scMET. |

scmet_simulate_diff | Simulate differential methylation data from scMET. |

scmet_to_sce | Convert from scmet to SingleCellExperiment object. |

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