Inter-sample condition variability is a key challenge of normalising ChIP-seq data. This implementation uses either spike-in or a second factor as a control for normalisation. Input can either be from 'DiffBind' or a matrix formatted for 'DESeq2'. The output is either a 'DiffBind' object or the default 'DESeq2' output. Either can then be processed as normal. Supporting manuscript Guertin, Markowetz and Holding (2017) <doi:10.1101/182261>.
|Author||Andrew N Holding|
|Bioconductor views||ChIPSeq Sequencing Software Technology|
|Maintainer||Andrew N Holding <email@example.com>|
|License||CC BY 4.0|
|Package repository||View on GitHub|
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