mf3 | R Documentation |
Compute the FIM for one individual given specific model(s), parameters, design and methods.
mf3(model_switch, xt, x, a, bpop, d, sigma, docc, poped.db)
model_switch |
A vector that is the same size as xt, specifying which model each sample belongs to. |
xt |
A vector of sample times. |
x |
A vector for the discrete design variables. |
a |
A vector of covariates. |
bpop |
The fixed effects parameter values. Supplied as a vector. |
d |
A between subject variability matrix (OMEGA in NONMEM). |
sigma |
A residual unexplained variability matrix (SIGMA in NONMEM). |
docc |
A between occasion variability matrix. |
poped.db |
A PopED database. |
As a list:
ret |
The FIM for one individual |
poped.db |
A PopED database |
Other FIM:
LinMatrixH()
,
LinMatrixLH()
,
LinMatrixL_occ()
,
calc_ofv_and_fim()
,
ed_laplace_ofv()
,
ed_mftot()
,
efficiency()
,
evaluate.e.ofv.fim()
,
evaluate.fim()
,
gradf_eps()
,
mf7()
,
mftot()
,
ofv_criterion()
,
ofv_fim()
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