# Just a few iterations, optimize on DOSE and sample times using the full FIM
out_1 <- RS_opt(poped.db,opt_xt=1,opt_a=1,rsit=3,fim.calc.type=0, out_file = "")
\dontrun{
RS_opt(poped.db)
RS_opt(poped.db,opt_xt=TRUE,rsit=100,compute_inv=F)
RS_opt(poped.db,opt_xt=TRUE,rsit=20,d_switch=0)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,d_switch=0,use_laplace=T)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,d_switch=0,use_laplace=T,laplace.fim=T)
## Different headers and footers of output
RS_opt(poped.db,opt_xt=TRUE,rsit=10,out_file="foo.txt")
output <- RS_opt(poped.db,opt_xt=TRUE,rsit=100,trflag=FALSE)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,out_file="")
RS_opt(poped.db,opt_xt=TRUE,rsit=10,header_flag=FALSE)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,footer_flag=FALSE)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,header_flag=FALSE,footer_flag=FALSE)
RS_opt(poped.db,opt_xt=TRUE,rsit=10,header_flag=FALSE,footer_flag=FALSE,out_file="foo.txt")
RS_opt(poped.db,opt_xt=TRUE,rsit=10,header_flag=FALSE,footer_flag=FALSE,out_file="")
}
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