(ICMg) and context-specific behavior (NetResponse) of interaction networks. ICMg is used to identify community structure in interaction networks;

Interaction Component Model for Gene Modules

Interaction Component Model (ICMg) can be used to find functional gene modules from either protein interaction data or from combinations of protein interaction and gene expression data. Run ICMg and cluster the nodes:

library(netresponse)
data(osmo)
res <- ICMg.combined.sampler(osmo$ppi, osmo$exp, C=10)
res$comp.memb <- ICMg.get.comp.memberships(osmo$ppi, res)
res$clustering <- apply(res$comp.memb, 2, which.max)

When using the ICMg algorithms, additionally cite Parkkinen et al. (2010).



antagomir/netresponse documentation built on March 30, 2023, 7:24 a.m.