Description Usage Arguments Value
compute per-variant imbalance statistics, including p-values and effect sizes
1 2 | compute_imbalance_statistics(counts_frame, null_shape1, null_shape2,
lsse_shape1, lsse_shape2, minimum_coverage = 10)
|
counts_frame |
data frame containing allele counts |
null_shape1 |
first shape parameter of the null distribution (from npbin) |
null_shape2 |
second shape parameter of the null distribution (from npbin) |
lsse_shape1 |
first shape parameter of the LSSE estimate |
lsse_shape2 |
second shape parameter of the LSSE estimate |
minimum_coverage |
minimum coverage level for filtering variants |
data frame, including allele counts and imbalance statistics
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