Description Usage Arguments Value
This file contains the primary code for the qusage methodology Author: Christopher Bolen Gur Yaari (c) 2013 Yale University. All rights reserved. but runs welch's approximation in C++.
1 2 | qusageCutArm(eset, labels, contrast, geneSets, pairVector = NULL,
var.equal = FALSE, filter.genes = FALSE, n.points = 2^12)
|
eset |
a matrix of log2(expression values), with rows of features and columns of samples. OR an object of class ExpressionSet |
labels |
vector of labels representing each column of eset. |
contrast |
a string describing which of the groups in 'labels' we want to compare. This is usually of the form 'trt-ctrl', where 'trt' and 'ctrl' are groups represented in 'labels'. |
geneSets |
a list of pathways to be compared. Each item in the list is a vector of names that correspond to the row names of eset. |
pairVector |
A vector of factors (usually just 1,2,3,etc.) describing the sample pairings. This is often just a vector of patient IDs or something similar. If not provided, all samples are assumed to be independent. |
var.equal |
a logical variable indicating whether to treat the two variances as being equal. If TRUE then the pooled variance is used to estimate the variance otherwise the Welch approximation is used. |
filter.genes |
a boolean indicating whether the genes in eset should be filtered to remove genes with low mean and sd. |
n.points |
The number of points to sample the convolution at. Passed to aggregateGeneSet |
qusage data array for welch's approx
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