WZda: Summary score statistics and associated asymptotic covariance...

In baolinwu/MetaSAT: Meta-analysis of variant-set association tests

Description

A list containing the summary statistics matrix (9x3) and the covariance matrix array (9x9x3)

Usage

WZda

Format

A list with two components

Us

9x3 matrix of summary score statistics (9 variants across 3 studies)

Vs

9x9x3 array of covariance matrix (9 variants across 3 studies)

References

Wu,B. and Zhao,H. (2018) Efficient and powerful meta-analysis of variant-set association tests using MetaSAT.

Wu,B., Guan,W. and Pankow,J.S. (2016) On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set. Ann. Hum. Genet., 80 (2), 123–135.

Wessel,J., Chu,A.Y., Willems,S.M. and others. (2015) Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications, 6, 5897.

Examples

data(WZda)
Us = WZda$Us; Vs = WZda$Vs
FESAT(Us,Vs)
HESAT(Us,Vs)
RESAT(Us,Vs)
RBAT(Us,Vs)

baolinwu/MetaSAT documentation built on May 13, 2019, 5:22 p.m.