getDrugGeneData: Function to generate heatmaps that show a drugs influence on...
In bhklab/CMapBox:

Description Usage Arguments Value Examples

This function returns a heat map that shows how a drug changes the expression of a set of genes, as determined by molecular profiles in the pharmacoSet supplied.

1	getDrugGeneData(drugPert, pharmSet, mDataType, drugName, genesOfInt)

`drugPert`	the drug perturbation signature of interest
`pharmSet`	the pharmacoSet used to generate the drug perturbation signature
`mDataType`	the type of molecular data to obtain from the PharmacoSet (see PharmacoGx::molecularProfiles)
`drugName`	the name of the drug one would like to inspect for its effect on the supplied genes
`genesOfInt`	a character vector containing the names of the genes one would like to observe the drugs effect on

a list containing 1. beforeDrugMat which is a matrix containing the expression levels for the genes before the drug was applied. 2. afterDrugMat which is a matrix containing the expression levels for the genes before the drug was applied. 3. geneChangePlot, which is a levelplot object showing the change in expression for the genes due to the drugs

1
2
3

data("drugPertEx")
#example in getSigGeneVolPlot function yields below genes
drivingGenes = c("ABCC5", "VPS28", "RPS6KA2", "TRIM2", "CD47", "MELK", "CDKN3", "GGH", "MCM7", "KIF2C")