rhoge.gw: Calculates genome-wide genetic correlation between two...
In bogdanlab/RHOGE: Genome-wide genetic correlation between two complex traits using TWAS effect-size estimates
Description
Calculates genome-wide genetic correlation between two complex traits using TWAS summary statistics.
Usage
1
rhoge.gw(trait1, trait2, n1, n2, p = 0.05, regions = grch37.eur.loci)
Arguments
trait1
data.frame-like, TWAS results for trait 1
trait2
data.frame-like, TWAS results for trait 2
n1
integer, sample-size for trait 1 GWAS
n2
integer, sample-size for trait 2 GWAS
p
double, nominal significance threshold for genome-wide RhoGE estimate (default=0.05)
regions
data.frame-like, Approximate independent regions. Requires columns (Chr, Start, Stop). Default is estimated blocks in Europeans.
bogdanlab/RHOGE documentation built on May 25, 2019, 3:24 p.m.
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Description
Calculates genome-wide genetic correlation between two complex traits using TWAS summary statistics.
Usage
1 | rhoge.gw(trait1, trait2, n1, n2, p = 0.05, regions = grch37.eur.loci)
|
Arguments
trait1 |
data.frame-like, TWAS results for trait 1 |
trait2 |
data.frame-like, TWAS results for trait 2 |
n1 |
integer, sample-size for trait 1 GWAS |
n2 |
integer, sample-size for trait 2 GWAS |
p |
double, nominal significance threshold for genome-wide RhoGE estimate (default=0.05) |
regions |
data.frame-like, Approximate independent regions. Requires columns (Chr, Start, Stop). Default is estimated blocks in Europeans. |
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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