Description Usage Arguments Value
For simply estimating the cell-type proportions, see estimate.cell.proportions.
1 2 | adjust.beta(B, top_n = 500, mc.cores = 2, cell.coefs = NULL,
omega.mix = NULL)
|
B |
matrix of beta values (n_probes * n_samples) rownames must be the illumina cg id or the chrom:position |
top_n |
number of probes from cell.coefs to use |
mc.cores |
number of cores to use for parallelization |
cell.coefs |
path to tab-delimited file containind DMR-probes for the cell types of interest. Ignored if omega.mix is provided. system.file("extdata", "houseman-dmrs.txt", package="celltypes450") |
omega.mix |
pre-specified matrix of cell-type coefficients. If not specified, this will be estimated from the data. |
matrix of adjusted beta values
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