mqmfind.marker: Fetch significant markers after permutation analysis

Description Usage Arguments Value Author(s) See Also Examples

Description

Fetch significant makers after permutation analysis. These markers can be used as cofactors for model selection in a forward stepwise approach.

Usage

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mqmfind.marker(cross, mqmscan = NULL, perm = NULL, alpha = 0.05, verbose=FALSE)

Arguments

cross

An object of class cross. See read.cross for details.

mqmscan

Results from either scanone or mqmscan

perm

a scanoneperm object

alpha

Threshold value, everything with significance < alpha is reported

verbose

Display more output on verbose=TRUE

Value

returns a matrix with at each row a significant marker (determined from the scanoneperm object) and with columns: markername, chr and pos (cM)

Author(s)

Ritsert C Jansen; Danny Arends; Pjotr Prins; Karl W Broman kbroman@biostat.wisc.edu

See Also

Examples

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data(multitrait)				#Use the multitrait dataset
cof <- mqmsetcofactors(multitrait,3)		#Set cofactors at each 3th marker
multitrait <- fill.geno(multitrait)
multitrait <- transformPheno(multitrait, 7)     #log transform the 7th phenotype
## Not run: result <- mqmpermutation(multitrait,scanfunction=mqmscan,cofactors=cof,pheno.col=7,n.perm=50,batchsize=10)	# Bootstrap 50 runs in batches of 10

f2perm <- mqmprocesspermutation(result)		        #Create a permutation object
summary(f2perm)				        #What LOD score is considered significant ?
marker <- mqmfind.marker(multitrait,result[[1]],f2perm)		#Find markers with a significant QTL effect (First run is original phenotype data)
marker						#Print it to the screen

byandell/qtl documentation built on May 13, 2019, 9:28 a.m.