CROSS_CRC_ADENOCARCINOMA_NATECOEVO_2018: Mutations and copy number from colorectal adenocarcinomas...

In caravagn/evoverse.datasets: Data released in the evoverse

Description

Mutations and copy number from colorectal adenocarcinomas (PMID: 30177804). n = 19 patients, multi-region whole-exome sequencing. Calls generated from Cross et al. (PMID: 30177804).

Usage

data(CROSS_CRC_ADENOCARCINOMA_NATECOEVO_2018)

Format

Data for the adenocarcinoma cohort by Cross et al. The data has been provided by WCh Cross, as of the Nature Ecology and Evolution paper (PMID: 30177804). Mutations are reported as present or absent in each one of the sequenced biopsies. All the data (calls, definition of driver events, etc.) is as provided by the authos, and as used in the paper Caravagna et al (PMID: 30171232) to show repeated evolution in breast cancers with REVOLVER.

References

Cross, W., Kovac, M., Mustonen, V., Temko, D., Davis, H., Baker, A.M., Biswas, S., Arnold, R., Chegwidden, L., Gatenbee, C. et al., 2018. The evolutionary landscape of colorectal tumorigenesis. Nature Ecology and Evolution, 2(10), p.1661. PMID 30177804.

Examples

data(CROSS_CRC_ADENOCARCINOMA_NATECOEVO_2018)
CROSS_CRC_ADENOCARCINOMA_NATECOEVO_2018

caravagn/evoverse.datasets documentation built on Feb. 16, 2020, 4:35 a.m.