alloc.def3: distributions derived. size allocation across regions by...

In carolinewei/apsurvival: Total sample size and its allocation for the MRCT

Description

distributions derived. size allocation across regions by maximizing conditional assurance probability by Definition 3 when regional treatment effects are sightly different.

Usage

alloc.def3(r0, alpha = 0.05, beta = 0.2, s, u, eps, pai, grid = 0.1)

Arguments

r0	True overall log hazard ratio
alpha	The risk of rejecting the null hypothesis H0:r0>=0 when it is really true
beta	The risk of failing to reject the null hypothesis H0:r0>=0 when it is really false
s	Number of regions participating in the MRCT
u	A vector presents ratios of true regional log hazard ratios to true overall log hazard ratio r=u*r0
eps	Significance level of not rejecting H0 in Definition 3
pai	The preserved proportion of overall treatment effect
grid	Grid interval of the grid research

Value

A list

Examples

set.seed(123)
Alloc3 <- alloc.def3(r0=log(0.7), alpha=0.05, beta=0.2, s=3, u=c(1.1,1,0.9), eps=0.3,
pai=1/3, grid=0.1)

carolinewei/apsurvival documentation built on Nov. 4, 2019, 8:44 a.m.