Description Usage Arguments Value Examples

distributions derived. size allocation across regions by maximizing conditional assurance probability by Definition 3 when regional treatment effects are sightly different.

1 | ```
alloc.def3(r0, alpha = 0.05, beta = 0.2, s, u, eps, pai, grid = 0.1)
``` |

`r0` |
True overall log hazard ratio |

`alpha` |
The risk of rejecting the null hypothesis H0:r0>=0 when it is really true |

`beta` |
The risk of failing to reject the null hypothesis H0:r0>=0 when it is really false |

`s` |
Number of regions participating in the MRCT |

`u` |
A vector presents ratios of true regional log hazard ratios to true overall log hazard ratio r=u*r0 |

`eps` |
Significance level of not rejecting H0 in Definition 3 |

`pai` |
The preserved proportion of overall treatment effect |

`grid` |
Grid interval of the grid research |

A list

1 2 3 |

carolinewei/apsurvival documentation built on Nov. 4, 2019, 8:44 a.m.

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