produceTablesSignifGroups: Produces tables with groups

Description Usage Arguments Details Value Author(s) References See Also Examples

Description

produceTablesSignifGroups produces tables with the significant groups. These tables include the names of the genes part of the groups, their respective frequency in the dataset, and the mu and corrected pvalue corresponding to each group.

Usage

1
produceTablesSignifGroups(signifGroups, mat, noToShow)

Arguments

signifGroups

result structure with the significant groups, as returned by either TiMEx or findSignifCliques

mat

binary alteration matrix, with rows representing patients and columns representing genes

noToShow

maximum number of groups to include in the table. Default is 30.

Details

This function summarizes information on the mutually exclusive groups identified by TiMEx in a dataset, as tables.

Value

list with as many elements as lengths of the identified mutually exclusive groups, containing tables with the significant groups for each size. Each list of this type further has two elements, fdr and bonf, corresponding to different multiple testing correction methods. Each element is a matrix, in which rows represent significantly mutually exclusive groups.

Author(s)

Simona Cristea, scristea@jimmy.harvard.edu

References

Constantinescu et al.: TiMEx: A Waiting Time Model for Mutually Exclusive Cancer Alterations. Bioinformatics (2015).

See Also

the wrapper function TiMEx for identifying mutually exclusive groups in a binary dataset with the TiMEx model.

Examples

1
2
3
4
# Produce tables on the output of TiMEx on the ovarian cancer dataset
data(ovarian)
data(ovarianOutput)
ovarianTables<-produceTablesSignifGroups(ovarianOutput,ovarian)

cbg-ethz/TiMEx documentation built on May 13, 2019, 1:50 p.m.