cbg-ethz/knockout: Statistical Analysis of High-Throughput Genetic Perturbation Screens
perturbatr does stage-wise analysis of large-scale genetic perturbation screens for integrated data sets consisting of multiple screens. For multiple integrated perturbation screens a hierarchical model that considers the variance between different biological conditions is fitted. The resulting list of gene effects is then further extended using a network propagation algorithm to correct for false negatives.
Getting started
Browse package contents
Package details |
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| Bioconductor views | CellBasedAssays ImmunoOncology Network Regression |
| Maintainer | Simon Dirmeier <simon.dirmeier@web.de> |
| License | GPL-3 |
| Version | 1.7.0 |
| URL | https://github.com/cbg-ethz/perturbatr |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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