gene_expression: Gene-expression measurements for various mutants of...

Description Usage Format Source Examples

Description

This dataset contains gene expression measurements for 59 genes of bacteriophage T7, measured for various modified T7 genomes.

Usage

1

Format

An object of class tbl_df (inherits from tbl, data.frame) with 413 rows and 7 columns.

Source

M. L. Paff, B. R. Jack, B. L. Smith, J. J. Bull, C. O. Wilke (2018). Combinatorial approaches to viral attenuation. bioRxiv 299180. http://dx.doi.org/10.1101/299180

Examples

 1
 2
 3
 4
 5
 6
 7
 8
 9
10
11
12
13
gene_expression %>% 
  filter(strain == "phi9v2" & background == "wt") %>%
  ggplot(aes(x=tpm_wt, y=tpm_mutant)) +
  geom_abline(slope = 1, color = "grey") +
  geom_text_repel(
    aes(label = label),
    nudge_y = -0.005,
    fontface = "italic",
    segment.color = NA) +
  geom_point() +
  scale_x_log10(limits = c(3e-4, .3), name = "wild-type RNA abundance (TPM)") + 
  scale_y_log10(limits = c(3e-4, .3), name = "mutant RNA abundance (TPM)") +
  coord_fixed()

clauswilke/dviz.supp documentation built on Aug. 25, 2020, 2:12 a.m.