compbiomed/ASSIGN: Adaptive Signature Selection and InteGratioN (ASSIGN)
Version 1.17.2

ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

Getting started

Package details

AuthorYing Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman
Bioconductor views Bayesian GeneExpression Pathways Software
MaintainerYing Shen <[email protected]>, W. Evan Johnson <[email protected]>, David Jenkins <[email protected]>, Mumtehena Rahman <[email protected]>
LicenseMIT + file LICENSE
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
compbiomed/ASSIGN documentation built on Aug. 11, 2018, 1:01 p.m.