In crhisto/SCDC: Bulk RNA-seq deconvolution by scRNA-seq with multi-reference datasets

knitr::opts_chunk$set(
  collapse = TRUE,
  comment = "#>",
  fig.path = "man/figures/README-",
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SCDC: Bulk Gene Expression Deconvolution by Multiple Single-Cell RNA Sequencing References

SCDC is a deconvolution method for bulk RNA-seq that leverages cell-type specific gene expressions from multiple scRNA-seq reference datasets. SCDC adopts an ENSEMBLE method to integrate deconvolution results from different scRNA-seq datasets that are produced in different laboratories and at different times, implicitly addressing the batch-effect confounding.

Installation

You can install the released version of SCDC from GitHub with:

if (!require("devtools")) {
  install.packages("devtools")
}
devtools::install_github("meichendong/SCDC")

Vignettes

Please see the vignettes page.

The SCDC paper is published at Briefings In Bioinformatics.

crhisto/SCDC documentation built on Dec. 19, 2021, 6:19 p.m.