relative_to_absolute_copy_number: Convert relative copy numbers to absolute copy numbers

In crukci-bioinformatics/rascal: Shiny app and functions for scaling relative copy number data to absolute values

Description

Convert relative copy numbers to absolute copy numbers based on the given ploidy and cellularity.

Usage

relative_to_absolute_copy_number(relative_copy_numbers, ploidy, cellularity)

Arguments

relative_copy_numbers	a numeric vector containing relative copy numbers, i.e. ratios of copy numbers to the average copy number.
ploidy	the tumour ploidy.
cellularity	the cellularity, i.e. the fraction of cells that are from the tumour.

Value

a numeric vector of absolute copy numbers.

Examples

relative_to_absolute_copy_number(c(0.98, 1.6, 1.23), 4.01, 0.77)

crukci-bioinformatics/rascal documentation built on Dec. 19, 2021, 6:21 p.m.