DE-class: An S4 class for simulating dose-titration study designs

In dcnorris/DTAT: Dose Titration Algorithm Tuning: a framework for dose individualization

Description

An S4 class for simulating dose-titration study designs

Slots

doses

A numeric vector of prospectively-determined discrete doses to trial.

units

A string indicating dose units, e.g. "mg/kg".

MTDi

A numeric vector of optimal doses for simulated study participants. Optionally a call to an r<distribution>(...) function which may be parsed to calculated the mtd_quantiles slot.

mtd_quantiles

A numeric vector of quantiles of the distribution from which the MTDi slot was simulated. Intended mainly to support visualization of this distribution, e.g. as an transparent overlay on the dose-survival plot. NULL in case MTDi is provided verbatim.

data

A data.frame with columns TODO.

stop_esc

integer TODO.

ds_conf_level

numeric TODO.

dose_drop_threshold

numeric TODO.

stop_esc_under

numeric TODO.

undo_esc_under

numeric TODO.

dcnorris/DTAT documentation built on May 7, 2019, 10:45 p.m.