mcode_db: MCODE function wrapper

Description Usage Arguments Details

View source: R/function_call_wrappers.R

Description

MCODE function wrapper

Usage

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mcode_db(
  input_name,
  ppi_name,
  to_db = TRUE,
  folder = NULL,
  hierarchy = 1,
  vwp = 0.5,
  haircut = F,
  fluff = F,
  fdt = 0.8,
  loops = T,
  deg_cutoff = 0.05,
  module_cutoff = 3.5,
  module_name,
  con
)

Arguments

input_name

Name of the input object in the database

ppi_name

Name of the PPI network in the database

to_db

Save result in database, default is TRUE

folder

If not saved in database, folder where to save the module as .rds

hierarchy

This parameter indicates how many hierarchy are included in the network, currently it can be 0, 1 or 2. Default value is 1.

vwp

Vertex weight percentage. Default value is 0.5.

haircut

Boolean value, whether to remove singly-connected nodes from clusters (TRUE) or not (FALSE).

fluff

Boolean value, whether to spand cluster cores by one neighbour shell outwards (TRUE) or not (FALSE).

fdt

Cluster density cutoff. Default value is 0.8.

loops

Boolean value, whether to include self-loops (TRUE) or not (FALSE).

deg_cutoff

p-value cutoff for differentialy expressed genes

module_cutoff

Minimal score for a module to be returned

module_name

Unique name for the module object when stored in database

con

Database connection obtained with connect_to_db function

Details

Retrieves a MODifieR input object from database by input_name and runs mcode method.


ddeweerd/MODifieRDB documentation built on Feb. 5, 2021, 1:50 a.m.