denisagniel/tcgsaseq: Time-Course Gene Set Analysis for RNA-Seq Data

Analyze RNA-seq data with variance component score test accounting for data heteroscedasticity through precision weights. Perform both gene-wise and gene set analyses, and can deal with longitudinal data. Method is detailed in: Agniel & Hejblum (2017) <doi: 10.1093/biostatistics/kxx005>, Variance component score test for time-course gene set analysis of longitudinal RNA-seq data, Biostatistics, 18(4):589-604.

install.packages("remotes")
remotes::install_github("denisagniel/tcgsaseq")