qtl2med-package: Mediation Analysis for qtl2
In dmgatti/qtl2med: Mediation Analysis for qtl2

Description Details Author(s) References See Also Examples

Given a quantitative trait locus (qtl), the data that produced the qtl peak and gene expression data for the same set of subjects, ask whether the expression of any of the genes explains a significant part of the variance. We do this by regressing the phenotype on covariates and the genotype at the QTL peak and comparing this to a model that adds the expression of one gene. When we do this across the genome, we often find several genes that reduce the LOD score. These genes are candidate mediators that may be influencing the phenotype.

The DESCRIPTION file: This package was not yet installed at build time.

Index: This package was not yet installed at build time.
~~ An overview of how to use the package, including the most important ~~ ~~ functions ~~

NA

Maintainer: NA

~~ Literature or other references for background information ~~

~~ Optional links to other man pages, e.g. ~~ ~~ <pkg> ~~