Man pages for dominicmagirr/dosecombo
Combination Dose Escalation

admissible_dosesFind doses which would not be 'too big' an increase
binom_2_bernTurn a short DLT data frame with n_dlt/n into a longer...
choose_priorFind prior parameters for an increasing logistic curve
combine_dosesChoose dose combinations to be investigated, and plot the...
combine_doses_trimChoose dose combinations to be investigated, and plot the...
combo_truthProduce a vector of "true" p(DLT) at each dose combination
compare_allGraphical comparison of a model-based design versus a...
compare_overall_nPlot the sample sizes of a series of simulated trials.
compare_over_targetPlot the number of patients treated above the 'target'...
compare_prop_dltsPlot the proportion of DLTs in a series of simulated trials.
compare_true_toxPlot the true toxicity probabilities at the selected doses
comparison_simSimulate model-based and rule-based trials, and compare...
create_combo_priorCreate a prior for combination dose response model from 2...
create_mono_priorCreate a prior for monotherapy dose response, similar to...
dose_gridCreate matrix of all possible dose combinations
dose_rowFind the row number of a dose combination of interest.
dosesCombine original and log doses in a single object
find_starting_doseFind the id number of the recommended starting dose
first_stepsPlot what posterior would look like after first cohort.
get_infoFind quantiles of p(DLT) and probabilites of toxicity
get_next_doseGet the next dose
get_prior_infoFind quantiles of p(DLT) and probabilites of toxicity
get_samplesUse JAGS to get simulations from posterior
next_stepsPlot what posterior would look like after first cohort.
plot_combo_dose_idDisplay the id number of each dose combination.
plot_contourPlot contours of p(overdose) and p(target toxicity).
plot_infoPlot the prior/posterior distribution for p(DLT) at all dose...
plot_route_through_dosesDisplay the id number of each dose combination with route...
plot_selectedPlot how often each dose combination is selected
plot_trialPlot the results of a simulated trial
plot_truthPlot the 'true' p(DLT) at all dose combinations
sim_studySimulate multiple studies and collect results
sim_trialSimulate a combination dose finding trial.
sum_simsSummarize results from simulation
dominicmagirr/dosecombo documentation built on May 6, 2019, 4:32 p.m.