combo_truth: Produce a vector of "true" p(DLT) at each dose combination

In dominicmagirr/dosecombo: Combination Dose Escalation

Description

Produce a vector of "true" p(DLT) at each dose combination

Usage

combo_truth(doses, ref_doses = c(75, 40), ref_probs = c(0.25, 0.2),
  other_doses = c(25, 10), other_probs = c(0.005, 0.005),
  odds_multiplier = 9)

Arguments

doses	A list containing doses on the original and log scale.
ref_doses	Vector of length 2. Doses of agent 1 and agent 2 used as reference for standardization. Does not have to match the reference doses in the 'doses' object.
ref_probs	Vector of length 2. Probability of DLT at "ref_doses".
other_doses	Vector of length 2. Doses of agent 1 and agent 2. Any choices valid, apart from the "ref_doses".
other_probs	Vector of length 2. Probability of DLT at "other_doses".
odds_multiplier	Interaction effect, equivalent to exp(eta). In the model, the odds of DLT at "ref_doses" gets multiplied by "odds_multiplier".

Value

A vector containing p(DLT) at each of the dose combinations in "doses".

dominicmagirr/dosecombo documentation built on May 6, 2019, 4:32 p.m.