Description Usage Arguments Value
Simulate a combination dose finding trial.
1 2 3 |
doses |
A list containing doses on the original and log scale. |
truth |
A vector of 'true' p(DLT)'s, corresponding to the rows of 'log_doses'. |
max_n_cohort |
The maximum number of cohorts. |
cohort_size |
Cohort size. |
starting_dose |
Starting dose. |
max_cohort_size |
Maximum size of cohort. If this is reached, and the max_n or max_p_target is reached then the trial can stop. |
max_n |
Maximum total sample size. If this is reached and the max_cohort_size is reached for recommended dose then the trial can stop. |
max_p_target |
Maximum probability of targeted toxicity. If this is reached and the max_cohort_size is reached for recommended dose then the trial can stop. |
add_random |
Should some randomness be added to choice of next dose? Default is FALSE. |
frac_target |
If randomness is added, how close to the 'best' dose is acceptable. Default is 75 percent of P(target toxicity). |
over_limit_end |
The safety limit to be applied at the end of the trial |
n_iter |
Number of iterations in MCMC. |
A vector containing the number of patients dosed, the number of dlts, and the recommended MTD.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.