data_nutlin: Nutlin-3 data set

View source: R/fct_datasets.R

data_nutlinR Documentation

Nutlin-3 data set

Description

Example data set containing sensitivity of 968 cell lines to the drug nutlin-3. Nutlin-3 is an MDM2 inhibitor, which leads to the reactivation of p53 and cell cycle arrest.

Usage

data_nutlin()

Format

A tibble with 968 rows and 6 columns.

Cell line

Common name of cell line

TCGA classification

Cancer type, annotated by The Cancer Genome Atlas

Tissue

Tissue of origin

Tissue sub-type

More detailed description of tumor type

IC50

Concentration of nutlin-3 (µM) required to inhibit cell growth by 50%

AUC

Area under the dose response curve

Source

The Genomics of Drug Sensitivity in Cancer Project: https://cancerrxgene.org


dwassarman/cellpanelr documentation built on Jan. 3, 2023, 8:27 a.m.