Description Usage Arguments Value
calc_mean_cov
takes as input a set of bws. Then uses the total AUC to
normalise coverage per sample and finally collapses the coverage for each
sample into a mean coverage.
1 | calc_mean_cov(bw_paths, aucs, target_auc, chr_to_filter)
|
bw_paths |
paths to bigwig files. |
aucs |
vector containing aucs matching the order of bigwig paths. |
target_auc |
total auc to normalise all samples to. E.g. 40e6 * 100 would be the estimated total auc for sample sequenced to 40 million reads of 100bp in length. |
chr_to_filter |
chrs to obtain mean coverage for. |
list of Rle objects. Each containing the mean coverage for an entire chromosome.
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