create_kappa_matrix: Create Kappa Statistics Matrix

In egeulgen/pathfindR: Enrichment Analysis Utilizing Active Subnetworks

Create Kappa Statistics Matrix

Description

Create Kappa Statistics Matrix

Usage

create_kappa_matrix(
  enrichment_res,
  use_description = FALSE,
  use_active_snw_genes = FALSE
)

Arguments

enrichment_res	data frame of pathfindR enrichment results. Must-have columns are 'Term_Description' (if use_description = TRUE) or 'ID' (if use_description = FALSE), 'Down_regulated', and 'Up_regulated'. If use_active_snw_genes = TRUE, 'non_Signif_Snw_Genes' must also be provided.
use_description	Boolean argument to indicate whether term descriptions (in the 'Term_Description' column) should be used. (default = FALSE)
use_active_snw_genes	boolean to indicate whether or not to use non-input active subnetwork genes in the calculation of kappa statistics (default = FALSE, i.e. only use affected genes)

Value

a matrix of kappa statistics between each term in the enrichment results.

Examples

sub_df <- example_pathfindR_output[1:3, ]
create_kappa_matrix(sub_df)

egeulgen/pathfindR documentation built on Feb. 1, 2024, 4:34 a.m.