federicogiorgi/vulcan: VirtUaL ChIP-Seq data Analysis using Networks
Version 0.99.37

Vulcan (VirtUaL ChIP-Seq Analysis through Networks) is a package that interrogates gene regulatory networks to infer cofactors significantly enriched in a differential binding signature coming from ChIP-Seq data. In order to do so, our package combines strategies from different BioConductor packages: DESeq for data normalization, ChIPpeakAnno and DiffBind for annotation and definition of ChIP-Seq genomic peaks, csaw to define optimal peak width and viper for applying a regulatory network over a differential binding signature.

Getting started

Package details

AuthorFederico M. Giorgi, Andrew N. Holding, Florian Markowetz
Bioconductor views ChIPSeq GeneExpression NetworkEnrichment SystemsBiology
MaintainerFederico M. Giorgi <[email protected]>
LicenseLGPL-3
Version0.99.37
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("devtools")
library(devtools)
install_github("federicogiorgi/vulcan")
federicogiorgi/vulcan documentation built on Sept. 29, 2017, 10:08 p.m.