l_psa: PSA object of the cost-effectiveness analysis decision model

In feralaes/cdx2cea: A cost-efectiveness analysis of testing stage II colon cancer patients for the absence of CDX2 biomarker followed by adjuvant chemotherapy

PSA object of the cost-effectiveness analysis decision model

Description

An object of class psa with PSA inputs and outputs for the Sick-Sicker model.

Usage

l_psa

Format

A list with 11 rows and 5 variables:

n_strategies

Number of strategies.

strategies

Strategy names.

n_sim

Number of PSA samples.

cost

A data frame with n_sim rows and n_strategies columns with the cost per strategy for all PSA samples.

effectiveness

A data frame with n_sim rows and n_strategies columns with the effectiveness per strategy for all PSA samples.

parameters

Survival target. A data frame of input parameters with n_sim rows and 15 columns:

• r_DieMets: Cancer mortality rate (CALIBRATED)

• r_RecurCDX2pos: Rate of recurrence in CDX2 positive patients (CALIBRATED)

• hr_RecurCDX2neg: Hazard ratio of recurrence in CDX2 negative vs positive patients (CALIBRATED)

• p_Mets: Proportion of recurrence being metastatic (CALIBRATED)

• p_CDX2neg: Proportion of CDX2-negative patients

• hr_Recurr_CDXneg_Rx: Hazard ratio for disease recurrence among patients with CDX2-negative under chemo versus CDX2-negative patients without chemotherapy.

• hr_Recurr_CDXpos_Rx: Hazard ratio for disease recurrence among patients with CDX2-positive under chemo versus CDX2-positive patients without chemotherapy.

• c_Chemo: Cost of chemotherapy

• c_ChemoAdmin: Cost of chemotherapy administration

• c_CRCStg2_init: Initial costs in CRC Stage II (minus chemo and chemo admin)

• c_CRCStg2_cont: Continuing costs in CRC Stage II

• c_CRCStg4_cont: Continuing costs in CRC Stage IV

• ic_DeathCRCStg2: Increase in cost when dying from cancer while in Stage II

• ic_DeathOCStg2: Increase in cost when dying from Other Causes (OC) while in Stage II

• c_Test: Cost of IHC staining

• u_Stg2: Utility of Stage II without chemo

• u_Stg2Chemo: Utility of Stage II with chemo

• u_Mets: Utility of metastatic recurrence state

parnames

A vector of strings with parameter names.

currency

A string with the currency.

feralaes/cdx2cea documentation built on April 7, 2024, 10:12 a.m.