covid19: COVID-19 RNA-seq dataset

In fernandoPalluzzi/SEMdata: Datasets for SEM-based network analysis using the SEMgraph R package

COVID-19 RNA-seq dataset

Description

Expression profiling through high-throughput sequencing (RNA-seq, Illumina NovaSeq 6000) of 72 young human patients (< 50 years old) with severe forms of COVID-19, from Carapito et al. (2022).

Usage

covid19

Format

covis19 is a data.frame of 15957 rows (genes) and 69 columns (subjects), including RSEM count data for 23 (C1-23) non-critical and 46 (P1-46) critical COVID-19 cases. The former group is composed by patients in a non-critical care ward under supplemental oxygen, while the latter included patients in the intensive care unit with Acute Respiratory Distress Syndrome (ARDS), as reported by Carapito et al. 2022.

Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE172114

References

Carapito R, Li R, Helms J, Carapito C et al. Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort. Sci Transl Med 2022 Jan 19;14(628):eabj7521. <https://doi.org/10.1126/scitranslmed.abj7521>

Examples

summary(covid19)
dim(covid19)

fernandoPalluzzi/SEMdata documentation built on June 27, 2022, 7:04 a.m.