LangmuirModel-class: S4 class of the SPR Langmuir model

Description Details Slots See Also

Description

Langmuir model object

Details

check the manual for the detailed model specifications http://

Slots

kon

numeric association rate constant

koff

numeric dissociation rate constant

analyteConcentrations

numeric vector for different analyte concentrations.

s_d

numeric standard deviation of the Gaussian noise. by default s_d=0, which there is no noise.

Rmax

numeric the maximum RUs levels at the infinite high analyte concentration. It is also the maximum level of ligand immobilized on the chip surface

associationLength

numeric the time period to run the association

dissociationLength

numeric the time period to run the dissociation

R0

numeric vector the starting RUs for the dissocaiton phase. optional

offset

the level shifted at the begining of the dissociation phase optional

Rligand

the levels of ligand immobilized on the chip surface. optional
If this one is set, then it assumes a variable "Rmax" model. Where Rmax for different run is not fixed but rather different due to some factors such as regeration in (Sensiq) or stochasticity (in BioRad Proteon). In this model, the immoblized ligand is not fixed from run to run, but the effienciency or conversion constant is fixed.
This is a vector contains same number of element as the analyteConc.

efficiency

the conversion constant for a "variable" Rmax model optional
see above for explanation.

See Also

ConformationalSelectionModel-class TwoStateModel-class InducedFitModel-class


ffeng23/SPRATS documentation built on May 16, 2019, 12:50 p.m.