An R package to characterize the Antibody Antigen interactions under the Two State model by surface plasmon resonance
This package is defined to run analysis of SPR data under the two state model to estimate mean equilibrium dissociation constant as well as the mean dissociation rate constant. It takes in the exported text input data. Output is estimated by non-linear regression. The modelling can be generilized to multi-state conditions. This package can also provide functions to run simulations for different models, such as Langmuir model, induced fit model, conformation selection model and two state model.
Please refer to the vignettes to see details.
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