msNoiseGen: Noise Generator
In flajole/MSdata: Mass-spectrometry data analysis package

Description Usage Arguments See Also

Generates background signal in replicate groups completely filled with missing values (NAs). To estimate global noise, the median [M] and the 95 are computed for replication groups with less than a half of measurements (minority rule). The standard error [SE] is estimated as 95 more than a half of measurements (majority rule) revealing a groupwise maximum peak height of less than [max]. The resulting global noise is considered as [M ± SE] (as mean and SE) and used to random generate values from a normal distribution constrained with the global noise parameter.