Man pages for friend1ws/pmsignature
Extracting characteristic mutation signatures from a set of mutation data.

alignmentSignatureFrom the list of Parameters from the getPMSignature function,...
bootPMSignatureObtain the standard error estimates for parameters for...
boundaryTurbo_FCheck whether the parameter F is within the appropriate range
boundaryTurbo_QCheck whether the parameter Q is within the appropriate range
calcPMSLikelihoodA function for calculating the log-likelihood from the data...
convertFromTurbo_FRestore the converted parameter F for turboEM
convertFromTurbo_QRestore the converted parameter Q for turboEM
convertSignatureMatrixToVectorthe function for converting the mutation signature matrix to...
convertToTurbo_FConvert the parameter F so that turboEM can treat
convertToTurbo_QConvert the parameter Q so that turboEM can treat
EstimatedParameters-classAn S4 class representing the estimated parameters
getBackgroudSignatureget mutation feature vector from context sequence data and...
getCosDistancethe function for calculating cosine distances between two...
getLogLikelihoodCCalculate the value of the log-likelihood for given...
getMembershipValueGet the values of estimated membership parameters
getMutationFeatureVectorGet mutation feature vector from context sequence data and...
getMutMembershipObtain the standard error estimates for parameters for...
getMutNumObtain somatic mutation count for each sample
getPMSignatureObtain the parameters for mutation signatures and memberships
getSignaturesForMultipleKGenerate the figure of mutation signature for multiple K...
getSignatureValueGet the values of estimated signatures
makeSimDataGenerate simulation data
MetaInformation-classAn S4 class to represent a mutation meta information common...
MutationFeatureData-classAn S4 class representing the mutation data
mySquareEMA function for estimating parameters using Squared EM...
PMSboundaryA functional for generating the function checking the...
readBGFileRead and format the background vector data
readMFVFileRead the raw mutation data with the mutation feature vector...
readMPFileRead the raw mutation data of Mutation Position Format.
updateBackgroudSignatureFileupdate the background signature file in the package...
updateMstepFQCUpdate the parameter F and Q (M-step in the EM-algorithm)
updatePMSParamA function for updating parameters using EM-algorithm
updateTheta_NormalizedCUpdate the auxiliary parameters theta and normalize them so...
visMembershipVisualize estimated membership parameters
visMembership2Visualize estimated membership parameters using ggvis
visPMS_fullvisualize probabisitic mutaiton signature for the full model
visPMSignatureVisualize estimated probabilistic mutation signatures
visPMS_indvisualize probabisitic mutaiton signature for the independent...
friend1ws/pmsignature documentation built on May 16, 2019, 3:27 p.m.