envData: The variables in the environment include an copy number...

In hanjunwei-lab/CNA2Subpathway: Identification of Dysregulated Subpathway Driven by Copy Number Alteration

Description

Identification of dysregulated subpathways driven by Copy Number aberrations(CNA). We firstly calculate the CNADEscore by copy number aberration and gene expression. Secondly, we constructing subpathways network that implicitly links subpathways through their common function and weight of the network based on the CNADEscore. Finally, we calculate an eigenvector centrality and the statistical significance of these subpathways is assessed using a bootstrap-based randomization method.

Format

An environment variable

Details

The environment variable includes the variable ampGene, delGene,CNAlabelresult,GEP,CNAP,GoInfo,SubPathwayInfo,GoSubPconGene,Jaccardscore,SubPathwaymapdata,CNAlabelresult,SubpathwayCNAresult,

Author(s)

Junwei [e-mail],Yuqi [e-mail], Baotong [e-mail]

hanjunwei-lab/CNA2Subpathway documentation built on Jan. 28, 2021, 6:56 p.m.